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1

Teicoplanin biosynthesis: unraveling the interplay of structural, regulatory, and resistance genes

Yushchuk, Oleksandr, Ostash, Bohdan, Truman, Andrew W., Marinelli, Flavia, Fedorenko, Victor

Journal:

Applied Microbiology and Biotechnology

Year:

2020

Language:

english

File:

PDF, 2.07 MB

english, 2020

2

Bacterial transglycosylase inhibitors

Bohdan Ostash, Suzanne Walker

Journal:

Current Opinion in Chemical Biology

Year:

2005

Language:

english

File:

PDF, 428 KB

english, 2005

3

Characterization of the post-assembly line tailoring processes in teicoplanin biosynthesis

Yushchuk, Oleksandr, Ostash, Bohdan, Pham, Thu H., Luzhetskyy, Andriy, Fedorenko, Victor, Truman, Andrew W, Horbal, Liliya

Journal:

ACS Chemical Biology

Year:

2016

Language:

english

File:

PDF, 953 KB

english, 2016

4

Genetic factors that influence moenomycin production in streptomycetes

Roman Makitrynskyy, Yuriy Rebets, Bohdan Ostash, Nestor Zaburannyi, Mariia Rabyk, Suzanne Walker, Victor Fedorenko

Journal:

Journal of Industrial Microbiology & Biotechnology

Year:

2010

Language:

english

File:

PDF, 453 KB

english, 2010

5

Cultivable actinomycetes from rhizosphere of birch ( Betula pendula ) growing on a coal mine dump in Silets, Ukraine

Ostash, Bohdan, Gren, Tetiana, Hrubskyy, Yaroslav, Tistechok, Stepan, Beshley, Stepan, Baranov, Volodymyr, Fedorenko, Victor

Journal:

Journal of Basic Microbiology

Year:

2014

Language:

english

File:

PDF, 123 KB

english, 2014

6

A gene cluster for the biosynthesis of moenomycin family antibiotics in the genome of teicoplanin producerActinoplanes teichomyceticus

Horbal, Liliya, Ostash, Bohdan, Luzhetskyy, Andriy, Walker, Suzanne, Kalinowski, Jorn, Fedorenko, Victor

Journal:

Applied Microbiology and Biotechnology

Year:

2016

Language:

english

File:

PDF, 762 KB

english, 2016

7

Development of a gene expression system for the uncommon actinomycete Actinoplanes rectilineatus NRRL B-16090

Yushchuk, Oleksandr, Homoniuk, Vitalina, Datsiuk, Yurij, Ostash, Bohdan, Marinelli, Flavia, Fedorenko, Victor

Journal:

Journal of Applied Genetics

Year:

2020

Language:

english

File:

PDF, 3.31 MB

english, 2020

8

Generation of New Landomycins by Combinatorial Biosynthetic Manipulation of the LndGT4 Gene of the Landomycin E Cluster in S. globisporus

Bohdan Ostash, Uwe Rix, Lily L.Remsing Rix, Tao Liu, Felipe Lombo, Andriy Luzhetskyy, Oleksandr Gromyko, Chenchen Wang, Alfredo F Braña, Carmen Méndez, José A Salas, Victor Fedorenko, Jürgen Rohr

Journal:

Chemistry & Biology

Year:

2004

Language:

english

File:

PDF, 628 KB

english, 2004

9

Evaluation of heterologous promoters for genetic analysis of Actinoplanes teichomyceticus—Producer of teicoplanin, drug of last defense

Horbal, Liliya, Kobylyanskyy, Anton, Yushchuk, Olexandr, Zaburannyi, Nestor, Luzhetskyy, Andriy, Ostash, Bohdan, Marinelli, Flavia, Fedorenko, Victor

Journal:

Journal of Biotechnology

Year:

2013

Language:

english

File:

PDF, 610 KB

english, 2013

10

Über das Acceptorsubstrat der C-Glycosyltransferase UrdGT2: drei Prejadomycin-C-glycoside aus einer konstruierten Mutante von Streptomyces globisporus 1912 ΔlndE(urdGT2)

Irfan Baig, Madan Kharel, Anton Kobylyanskyy, Lili Zhu, Yuriy Rebets, Bohdan Ostash, Andriy Luzhetskyy, Andreas Bechthold, Victor A. Fedorenko, Jürgen Rohr

Journal:

Angewandte Chemie

Year:

2006

Language:

german

File:

PDF, 234 KB

german, 2006

11

Insights into naturally minimisedStreptomyces albusJ1074 genome

Zaburannyi, Nestor, Rabyk, Mariia, Ostash, Bohdan, Fedorenko, Victor, Luzhetskyy, Andriy

Journal:

Year:

2014

Language:

english

File:

PDF, 850 KB

english, 2014

12

Identification ofStreptomyces coelicolorM145 genomic region involved in biosynthesis of teichulosonic acid–cell wall glycopolymer

Ostash, Bohdan, Shashkov, Alexander, Streshinskaya, Galina, Tulâskaya, Elena, Baryshnikova, Lidiya, Dmitrenok, Andrey, Dacyuk, Yuriy, Fedorenko, Victor

Journal:

Folia Microbiologica

Year:

2014

Language:

english

File:

PDF, 477 KB

english, 2014

13

Generation of Novel Landomycins M and O through Targeted Gene Disruption

Andriy Luzhetskyy, Lili Zhu, Miranda Gibson, Marta Fedoryshyn, Clemens Dürr, Carsten Hofmann, Dirk Hoffmeister, Bohdan Ostash, Cynthia Mattingly, Val Adams, Victor Fedorenko, Jürgen Rohr, Andreas Bech

Journal:

Year:

2005

Language:

english

File:

PDF, 86 KB

english, 2005

14

ABC transporter genes fromStreptomyces ghanaensismoenomycin biosynthetic gene cluster: roles in antibiotic production and export

Bohdan Ostash, Emma Doud, Suzanne Walker

Journal:

Archives of Microbiology

Year:

2012

Language:

english

File:

PDF, 359 KB

english, 2012

15

Genome Engineering Approaches to Improve Nosokomycin A Production by Streptomyces ghanaensis B38.3

Kuzhyk, Yuriy, Lopatniuk, Maria, Luzhetskyy, Andriy, Fedorenko, Victor, Ostash, Bohdan

Journal:

Indian Journal of Microbiology

Year:

2018

Language:

english

File:

PDF, 433 KB

english, 2018

16

Regulation of teicoplanin biosynthesis: refining the roles of tei cluster-situated regulatory genes

Yushchuk, Oleksandr, Horbal, Liliya, Ostash, Bohdan, Marinelli, Flavia, Wohlleben, Wolfgang, Stegmann, Evi, Fedorenko, Victor

Journal:

Applied Microbiology and Biotechnology

Year:

2019

Language:

english

File:

PDF, 2.09 MB

english, 2019

17

Role of GntR Family Regulatory Gene SCO1678 in Gluconate Metabolism in Streptomyces coelicolor M145

Tsypik, Olga, Makitrynskyy, Roman, Bera, Agnieszka, Song, Lijiang, Wohlleben, Wolfgang, Fedorenko, Victor, Ostash, Bohdan

Journal:

BioMed Research International

Year:

2017

Language:

english

File:

PDF, 2.60 MB

english, 2017

18

Novel teichulosonic acid from cell wall of Streptomyces coelicolor M145

Alexander S. Shashkov, Bohdan E. Ostash, Victor A. Fedorenko, Galina M. Streshinskaya, Elena M. Tul’skaya, Sof’ya N. Senchenkova, Lidiya M. Baryshnikova, Ludmila I. Evtushenko

Journal:

Carbohydrate Research

Year:

2012

Language:

english

File:

PDF, 667 KB

english, 2012

19

A Streamlined Metabolic Pathway for the Biosynthesis of Moenomycin A

Bohdan Ostash, Alan Saghatelian, Suzanne Walker

Journal:

Chemistry & Biology

Year:

2007

Language:

english

File:

PDF, 833 KB

english, 2007

20

An ABC transporter encoding genelndWconfers resistance to landomycin E

Iryna Ostash, Yuriy Rebets, Bohdan Ostash, Anton Kobylyanskyy, Maksym Myronovskyy, Tatsunosuke Nakamura, Suzanne Walker, Victor Fedorenko

Journal:

Archives of Microbiology

Year:

2008

Language:

english

File:

PDF, 295 KB

english, 2008

21

Complete Characterization of the Seventeen Step Moenomycin Biosynthetic Pathway

Ostash, Bohdan, Doud, Emma H., Lin, Cecilie, Ostash, Iryna, Perlstein, Deborah L., Fuse, Shinichiro, Wolpert, Manuel, Kahne, Daniel, Walker, Suzanne

Journal:

Year:

2009

Language:

english

File:

PDF, 2.96 MB

english, 2009

22

Streptomyces ghanaensispleiotropic regulatory genewblAghinfluences morphogenesis and moenomycin production

Mariia Rabyk, Bohdan Ostash, Yurij Rebets, Suzanne Walker, Victor Fedorenko

Journal:

Biotechnology Letters

Year:

2011

Language:

english

File:

PDF, 321 KB

english, 2011

23

A putative proteinase gene is involved in regulation of landomycin E biosynthesis in Streptomyces globisporus 1912

Lilia Dutko, Yuriy Rebets, Bohdan Ostash, Andriy Luzhetskyy, Andreas Bechthold, Tatsunosuke Nakamura, Victor Fedorenko

Journal:

FEMS Microbiology Letters

Year:

2006

Language:

english

File:

PDF, 145 KB

english, 2006

24

The molecular biology of moenomycins: towards novel antibiotics based on inhibition of bacterial peptidoglycan glycosyltransferases

Ostash, Bohdan, Doud, Emma, Fedorenko, Victor

Journal:

Biological Chemistry

Year:

2010

Language:

english

File:

PDF, 144 KB

english, 2010

25

Cell wall glycopolymers ofStreptomycesalbus,StreptomycesalbidoflavusandStreptomyces pathocidini

Shashkov, Alexander S., Streshinskaya, Galina M., Tul’skaya, Elena M., Senchenkova, Sophia N., Baryshnikova, Lidia M., Dmitrenok, Andrey S., Ostash, Bohdan E., Fedorenko, Victor A.

Journal:

Antonie van Leeuwenhoek

Year:

2016

Language:

english

File:

PDF, 1.68 MB

english, 2016

26

Analysis of Streptomyces ghanaensis ATCC14672 gene SSFG_07725 for putative γ-butyrolactone synthase

Kuzhyk, Yuriy, Mutenko, Halyna, Fedorenko, Victor, Ostash, Bohdan

Journal:

Folia Microbiologica

Year:

2018

Language:

english

File:

PDF, 893 KB

english, 2018

27

Heterologous AdpA transcription factors enhance landomycin production in Streptomyces cyanogenus S136 under a broad range of growth conditions

Yushchuk, Oleksandr, Ostash, Iryna, Vlasiuk, Iryna, Gren, Tetiana, Luzhetskyy, Andriy, Kalinowski, Joern, Fedorenko, Victor, Ostash, Bohdan

Journal:

Applied Microbiology and Biotechnology

Year:

2018

Language:

english

File:

PDF, 1.25 MB

english, 2018

28

Genetic insights into the mechanism of teicoplanin self-resistance in Actinoplanes teichomyceticus

Yushchuk, Oleksandr, Homoniuk, Vitalina, Ostash, Bohdan, Marinelli, Flavia, Fedorenko, Victor

Journal:

The Journal of Antibiotics

Year:

2020

File:

PDF, 752 KB

2020

29

Expression of the regulatory protein LndI for landomycin E production in Streptomyces globisporus 1912 is controlled by the availability of tRNA for the rare UUA codon

Yuriy V. Rebets, Bohdan O. Ostash, Masahiro Fukuhara, Tatsunosuke Nakamura, Victor O. Fedorenko

Journal:

FEMS Microbiology Letters

Year:

2006

Language:

english

File:

PDF, 439 KB

english, 2006

30

Coordination of export and glycosylation of landomycins in Streptomyces cyanogenus S136

Iryna Ostash, Bohdan Ostash, Andriy Luzhetskyy, Andreas Bechthold, Suzanne Walker, Victor Fedorenko

Journal:

FEMS Microbiology Letters

Year:

2008

Language:

english

File:

PDF, 283 KB

english, 2008

31

The Use of the Rare TTA Codon in Streptomyces Genes: Significance of the Codon Context?

Silov, Serhii, Zaburannyi, Nestor, Anisimova, Maria, Ostash, Bohdan

Journal:

Indian Journal of Microbiology

Year:

2020

File:

PDF, 688 KB

2020

32

Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics

Wenjun Zhang, Bohdan Ostash and Christopher T. Walsh

Journal:

Proceedings of the National Academy of Sciences

Year:

2010

Language:

english

File:

PDF, 1.40 MB

english, 2010

33

Landomycin biosynthesis and its regulation in Streptomyces

Yushchuk, Oleksandr, Kharel, Madan, Ostash, Iryna, Ostash, Bohdan

Journal:

Applied Microbiology and Biotechnology

Year:

2019

Language:

english

File:

PDF, 1.98 MB

english, 2019

34

Function oflanIin regulation of landomycin A biosynthesis inStreptomyces cyanogenusS136 and cross-complementation studies withStreptomycesantibiotic regulatory proteins encoding genes

Yuriy Rebets, Lilia Dutko, Bohdan Ostash, Andriy Luzhetskyy, Olexandr Kulachkovskyy, Toshio Yamaguchi, Tatsunosuke Nakamura, Andreas Bechthold, Victor Fedorenko

Journal:

Archives of Microbiology

Year:

2008

Language:

english

File:

PDF, 456 KB

english, 2008

35

MoeH5: a natural glycorandomizer from the moenomycin biosynthetic pathway

Ostash, Bohdan, Campbell, Jennifer, Luzhetskyy, Andriy, Walker, Suzanne

Journal:

Molecular Microbiology

Year:

2013

Language:

english

File:

PDF, 3.22 MB

english, 2013

36

Genomic Insights into Evolution of AdpA Family Master Regulators of Morphological Differentiation and Secondary Metabolism in Streptomyces

Rabyk, Mariia, Yushchuk, Oleksandr, Rokytskyy, Ihor, Anisimova, Maria, Ostash, Bohdan

Journal:

Journal of Molecular Evolution

Year:

2018

Language:

english

File:

PDF, 3.58 MB

english, 2018

37

The methodology of evaluation and monitoring of the fatigue fracture at macrocrack initiation stage

Chepil, Roman, Stankevych, Olena, Ostash, Orest, Klym, Bohdan

Journal:

Procedia Structural Integrity

Year:

2019

Language:

english

File:

PDF, 880 KB

english, 2019

38

Function of lanGT3, a Glycosyltransferase Gene Involved in Landomycin A Biosynthesis

Andriy Luzhetskyy, Tao Liu, Marta Fedoryshyn, Bohdan Ostash, Viktor Fedorenko, Jürgen Rohr, Andreas Bechthold

Journal:

Year:

2004

Language:

english

File:

PDF, 126 KB

english, 2004

39

Decoding options and accuracy of translation of developmentally regulated UUA codon in Streptomyces: bioinformatic analysis

Rokytskyy, Ihor, Koshla, Oksana, Fedorenko, Victor, Ostash, Bohdan

Journal:

Year:

2016

Language:

english

File:

PDF, 1.14 MB

english, 2016

40

Properties of Streptomyces albus J1074 mutant deficient in tRNALeu UAA gene bldA

Koshla, Oksana, Lopatniuk, Maria, Rokytskyy, Ihor, Yushchuk, Oleksandr, Dacyuk, Yuriy, Fedorenko, Victor, Luzhetskyy, Andriy, Ostash, Bohdan

Journal:

Archives of Microbiology

Year:

2017

Language:

english

File:

PDF, 1.06 MB

english, 2017

41

Analysis of Streptomyces coelicolor M145 genes SCO4164 and SCO5854 encoding putative rhodaneses

Gren, Tetiana, Ostash, Bohdan, Babiy, Volodymyr, Rokytskyy, Ihor, Fedorenko, Victor

Journal:

Folia Microbiologica

Year:

2017

Language:

english

File:

PDF, 499 KB

english, 2017

42

Manipulating the regulatory genes for teicoplanin production inActinoplanes teichomyceticus

Lilia Horbal, Nestor Zaburannyy, Bohdan Ostash, Sergiy Shulga, Victor Fedorenko

Journal:

World Journal of Microbiology and Biotechnology

Year:

2012

Language:

english

File:

PDF, 287 KB

english, 2012

43

On the Acceptor Substrate of C-Glycosyltransferase UrdGT2: Three Prejadomycin C-Glycosides from an Engineered Mutant of Streptomyces globisporus 1912 ΔlndE(urdGT2)

Irfan Baig, Madan Kharel, Anton Kobylyanskyy, Lili Zhu, Yuriy Rebets, Bohdan Ostash, Andriy Luzhetskyy, Andreas Bechthold, Victor A. Fedorenko, Jürgen Rohr

Journal:

Angewandte Chemie International Edition

Year:

2006

Language:

english

File:

PDF, 234 KB

english, 2006

44

The pathway-specific regulatory genes,tei15andtei16, are the master switches of teicoplanin production inActinoplanes teichomyceticus

Horbal, Liliya, Kobylyanskyy, Anton, Truman, Andrew W., Zaburranyi, Nestor, Ostash, Bohdan, Luzhetskyy, Andriy, Marinelli, Flavia, Fedorenko, Victor

Journal:

Applied Microbiology and Biotechnology

Year:

2014

Language:

english

File:

PDF, 1.84 MB

english, 2014

45

Genetic analysis of Streptomyces albus J1074 mia mutants suggests complex relationships between post-transcriptional tRNAXXA modifications and physiological traits

Koshla, Oksana, Kravets, Volodymyr, Dacyuk, Yuriy, Ostash, Iryna, SÃ¼ssmuth, Roderich, Ostash, Bohdan

Journal:

Folia Microbiologica

Year:

2020

File:

PDF, 1.10 MB

2020

46

Moenomycin family antibiotics: chemical synthesis, biosynthesis, and biological activity

Ostash, Bohdan, Walker, Suzanne

Journal:

Natural Product Reports

Year:

2010

Language:

english

File:

PDF, 1.02 MB

english, 2010

47

Structural Analysis of the Contacts Anchoring Moenomycin to Peptidoglycan Glycosyltransferases and Implications for Antibiotic Design

Yuan, Yanqiu, Fuse, Shinichiro, Ostash, Bohdan, Sliz, Piotr, Kahne, Daniel, Walker, Suzanne

Journal:

ACS Chemical Biology

Year:

2008

Language:

english

File:

PDF, 1.26 MB

english, 2008

48

Identification and characterization of Streptomyces ghanaensis ATCC14672 integration sites for three actinophage-based plasmids

Bohdan Ostash, Roman Makitrinskyy, Suzanne Walker, Victor Fedorenko

Journal:

Year:

2009

Language:

english

File:

PDF, 300 KB

english, 2009

49

TheadpA-like regulatory gene fromActinoplanes teichomyceticus:in silicoanalysis and heterologous expression

Ostash, Bohdan, Yushchuk, Oleksandr, Tistechok, Stepan, Mutenko, Halyna, Horbal, Lilia, Muryn, Andriy, Dacyuk, Yuriy, Kalinowski, Jorn, Luzhetskyy, Andriy, Fedorenko, Victor

Journal:

World Journal of Microbiology and Biotechnology

Year:

2015

Language:

english

File:

PDF, 569 KB

english, 2015

50

ChemInform Abstract: Moenomycin Family Antibiotics: Chemical Synthesis, Biosynthesis, and Biological Activity

Bohdan Ostash, Suzanne Walker

Journal:

Year:

2011

File:

PDF, 20 KB

2011

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